Development of health-related quality of life and subjective health complaints in adults born extremely preterm: a longitudinal cohort study

Table 3 Pooled data of self-reported functional health and well-being at 24 and 34 year of age in subjects born extremely preterm and age- and gender matched term-born controls using the SF-36 questionnaire^a

	Unadjusted^b Mean difference	Adjusted^c Mean difference
Response variable SF-36	EP-born verus Term-born estimate with 95% CI	EP-born versus Term-born estimate with 95% CI
Physical Functioning	− 8.93 ( − 14.56, − 3.30)**	− 1.60 ( − 7.18, 3.98)
Role Physical	− 5.54 ( − 15.11, 4.02)	− 0.98 ( − 11.00, 9.04)
Bodily Pain	− 8.80 ( − 16.48, − 1.13)**	− 2.81 ( − 11.13, 5.50)
General Health	− 7.23 ( − 13.08, − 1.39)**	− 5.94 ( − 13.19, 1.31)
Vitality	− 11.15 ( − 16.84, − 5.47)***	− 7.34 ( − 14.08, − 0,61)*
Social Functioning	− 11.97 ( − 19.55, − 4.40)**	− 10.11 ( − 18.10, − 2.12)*
Role Emotional	− 22.11 ( − 33.19, 11.04)***	− 15.48 ( − 27.40, − 3.55)**
Mental Health	− 8.83 ( − 13.86, − 3.79)***	− 6.12 ( − 11.87, − 0.36)*

CI confidence interval EP extremely preterm SD standard deviation
^*p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001
^aSF-36: Short Form Health Survey-36, with possible domain scores from 0 to 100, higher score indicates better functional health and well-being
^bMixed effects linear models including EP-born and term-born and age group. No significant difference between age 24 and 34 was found and therefore the results without age in the model are reported to increase the statistical power
^cMixed effects linear models adjusted for gender, education level, employment status and age were used in the model to assess differences in the SF-36 scores between 24 and 34 years, and between the groups at each age, including a group by age interaction
^dCollege/University under or over 4 years
^eNot working/retirement income or working

ISSN: 1477-7525