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Table 2 statistical analysis of domains in PROMIS-25, PedsQL 4.0, and EQ-5D-Y-3 L

From: Measurement properties of the EQ-5D-Y-3L, PedsQL 4.0, and PROMIS-25 Profile v2.0 in pediatric patients with spinal muscular atrophy

 

Mean (SD)

Median

Min (%)

Max (%)

Theoretical range

Mean value from the other Chinese population

PROMIS-25

      

Physical function

24.3 (5.5)

23.1

20.1 (41.3)

57.1 (0.8)

20.1–57.1

42.5(17.2)

Anxiety

53.5 (9.9)

54.8

35.6 (13.8)

79.5 (1.1)

35.6–79.5

49.5(10.9)

Depressive symptoms

53.3 (8.5)

54.6

37.7 (15.7)

78.7 (0.3)

37.7–78.7

50.2(10.2)

Fatigue

55.9 (9.0)

56.5

35.4 (7.7)

77.6 (1.7)

35.4–77.6

51.7(10.4)

Peer relationships

43.4 (8.6)

42.6

23.0 (2.2)

61.1 (9.9)

23-61.1

43.2(10.5)

Pain impact

49.9 (10.2)

49.3

36.7 (28.9)

67.7 (1.1)

36.7–74

49.3(10.1)

Pain Intensity

1.9 (2.0)

1.0

0 (31.1)

10 (0.3)

0–10

2.8(2.7)

Level sum score

58.9 (17.7)

59

24(0.3)

88(0.3)

25–125

-

PedsQL 4.0

      

Physical functioning score

7.2 (16.8)

0

0.0 (67.8)

75.0 (3.3)

0-100

87.3(9.8)

Emotional functioning score

68.4 (19.2)

65

0.0 (0.6)

100.0 (15.4)

0-100

83.0(15)

Social functioning score

51.3 (19.0)

50

0.0 (1.1)

100.0 (3.9)

0-100

90.0(12.9)

School functioning score

67.3 (16.7)

65

20.0 (0.3)

100.0 (3.0)

0-100

85.2(13.3)

Overall score

29.8 (13.9)

28.3

0(0.6)

87.5(0.6)

0-100

-

EQ-5D-Y-3 L

      

Index value

0.52 (0.17)

0.51

-0.09 (1.1)

0.99 (1.1)

-0.088-1

-

EQ VAS score

55.5 (24.6)

60

0.0 (1.4)

100.0 (2.8)

0-100

-