Measurement properties of the EQ-5D-Y-3L, PedsQL 4.0, and PROMIS-25 Profile v2.0 in pediatric patients with spinal muscular atrophy

Table 5 Correlations of similar dimensions/overall scores between measures

Dimension	Dimension	ρ / r^a	p-value
EQ-5D-Y-3 L	PROMIS-25
Walking about	Mobility	-0.61	< 0.001
Having pain or discomfort	Pain interference	0.48	< 0.001
Feeling worried, sad, or unhappy	Depressive symptoms	0.57	< 0.001
Feeling worried, sad, or unhappy	Anxiety	0.53	< 0.001
EQ-5D-Y-3 L	PedsQL 4.0
Walking about	Physical functioning	-0.61	< 0.001
Looking after myself	Physical functioning	-0.51	< 0.001
Doing usual activities	Social functioning	-0.33	< 0.001
Feeling worried, sad, or unhappy	Emotional functioning	-0.55	< 0.001
PedsQL 4.0	PROMIS-25
Physical functioning	Mobility	0.52	< 0.001
Emotional functioning	Anxiety	-0.68	< 0.001
Emotional functioning	Depressive symptoms	-0.67	< 0.001
Social functioning	Peer relationships	0.46	< 0.001
School functioning	Peer relationships	0.28	< 0.001
EQ-5D-Y-3 L	PedsQL 4.0
Index value	Overall score	0.56	< 0.001
EQ VAS	Overall score	0.25	< 0.001
EQ-5D-Y-3 L	EQ-5D-Y-3 L
Index value	EQ VAS	0.34	< 0.001
EQ-5D-Y-3 L	PROMIS-25
Index value	Level sum score	-0.26	< 0.001
EQ VAS	Level sum score	-0.2	< 0.001
PedsQL 4.0	PROMIS-25
Overall score	Level sum score	-0.32	< 0.001

a. For the comparisons between dimensions, the ρ was reported. For the comparisons between index value or overall scores, the r was reported

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