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Table 1 Anchor and clinical change group descriptions

From: Estimating the minimally important difference for the EQ-5D-5L and EORTC QLQ-C30 in cancer

Anchor

Description

Clinical change group

ECOG

The ECOG is a clinical measure with 5 grades of functioning that range from 0 to 5, where 0 indicates that a patient is fully active, 4 suggests that a patient is completely disabled, and 5 represents death.

A positive/negative change in the score of 1 grade on the scale of 0–5 represented the minimal expected change [22].

EQ-VAS

Patient self-reported general health question on a scale ranging from 0, which indicates the worst health you can imagine, to 100, which represents the best health you can imagine.

A positive/negative change in the score in the range of 7–10 points on the VAS scale of 0-100 [14].

EORTC QLQ-C30 item 29

Item 29 of the QLQ-C30 questionnaire asks respondents to self-report their overall health during the past week on a scale that ranges from 1, which indicates very poor, to 7, which represents excellent.

A positive/negative change in the score of 1 point on the scale of 1–7 [23]

EORTC QLQ-C30 item 29

Item 30 of the QLQ-C30 questionnaire asks respondents to self-report their quality of life during the past week on a scale that ranges from 1, which indicates very poor, to 7, which represents excellent.

A positive/negative change in the score of 1 point on the scale of 1–7 [23]

  1. ECOG, Eastern Cooperative Oncology Group; EORTC QLQ-C30, European Organisation for Research and Treatment of Cancer Quality of life Questionnaire Core 30; EQ-VAS, EuroQol Visual Analogue Scale