Estimating the minimally important difference for the EQ-5D-5L and EORTC QLQ-C30 in cancer

Table 4 Base-case correlations between EORTC QLQ-C30 and external anchors

Scale	ECOG	EQ-VAS	Q29 (Overall health)	Q30 (QLQ-C30 quality of life item)
PF	-0.48	0.61	0.6	0.58
RF	-0.41	0.64	0.63	0.63
EF	-0.17	0.49	0.49	0.52
CF	-0.24	0.47	0.46	0.46
SF	-0.35	0.58	0.57	0.62
FA	-0.38	0.66	0.67	0.64
NV	-0.24	0.36	0.37	0.37
PA	-0.25	0.56	0.58	0.55
DY	-0.25	0.43	0.44	0.44
SL	-0.17	0.4	0.42	0.42
AP	-0.30	0.43	0.44	0.43
CO	-0.17	0.27	0.27	0.25
DI	-0.12	0.2	0.23	0.22
QL	-0.34	-0.11	n/a	n/a

AP, appetite loss; CF, cognitive functioning; CO, constipation; DI, diarrhoea; DY, dyspnoea; ECOG, Eastern Cooperative Oncology Group; EF, emotional functioning; EORTC QLQ-C30, European Organisation for Research and Treatment of Cancer Quality of life Questionnaire Core 30; EQ-5D-5LEQ-VAS, EuroQol Visual Analogue Scale; FA, fatigue; NV, nausea/vomiting; PA, pain; PF, physical function; QL, global health status/quality of life; RF, role functioning; SF, social functioning; SL, insomnia
Bold figures satisfy the threshold (|r| > 0.30)

ISSN: 1477-7525