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Table 1 Baseline patient characteristics

From: A sex-oriented analysis concerning skeletal muscle quantity and quality and associations to quality of life in hospitalized patients with cirrhosis

 

Patients

P

All n = 382 (100%)

Male n = 190 (49.7%)

Female n = 192 (50.3%)

Age (years)

61.9 (10.30)

59.9 (10.53)

63.9 (9.69)

 < 0.001

Body composition parameters

 BMI, kg/m2

24.7 (4.90)

25.1 (4.87)

24.3 (4.90)

0.098

 VATI, cm2/m2

40.2 (26.2, 60.6)

43.2 (28.4, 63.5)

37.5 (24.6, 58.6)

0.167

 SATI, cm2/m2

44.1 (30.6, 68.5)

38.1 (25.3, 54.8)

53.6 (33.3, 79.9)

 < 0.001

 SMI, cm2/m2

45.5 (38.4, 52.3)

48.8 (41.4, 55.1)

42.2 (36.4, 48.7)

 < 0.001

 Sarcopenia, n (%)

96 (25.1)

77 (40.5)

19 (9.9)

 < 0.001

 IMAC

-0.54 (-0.71, -0.44)

-0.58 (-0.78, -0.47)

-0.52 (-0.66, -0.42)

 < 0.001

 Myosteatosis, n (%)

61 (16.0)

29 (15.3)

32 (16.7)

0.708

CTP classification, n (%)

 

0.318

 A

127 (33.2)

57 (30.0)

70 (36.5)

 

 B

200 (52.4)

102 (53.7)

98 (51.0)

 

 C

55 (14.4)

31 (16.3)

24 (12.5)

 

Etiology, n (%)

 

 < 0.001

 HBV/HCV

105 (27.4)

56 (26.8)

49 (22.9)

 

 Alcohol

84 (22.0)

82 (43.2)

2 (1.0)

 

 Autoimmune/Cholestasis

96 (27.7)

28 (6.8)

68 (48.4)

 

 MAFLD/Cryptogenic

97 (25.4)

24 (23.2)

73 (27.6)

 

MELD score

9.2 (7.3, 11.6)

9.1 (5.4, 11.8)

9.3 (8.1, 11.5)

0.082

MELD-Na score

9.5 (7.50 12.1)

9.5 (6.1, 12.6)

9.4 (8.1, 11.7)

0.541

AST (U/L)

32.0 (22.0, 47.8)

32.0 (21.0, 47.8)

32.0 (22.0, 49.0)

0.649

ALT (U/L)

23.0 (16.0, 36.3)

23.0 (16.0, 36.3)

23.0 (15.0, 36.3)

0.880

Total bilirubin (µmol/L)

21.6 (14.0, 33.2)

21.6 (13.7, 33.3)

21.6 (14.2, 33.4)

0.750

Albumin (g/L)

29.0 (25.0, 33.0)

28.0 (26.0, 33.0)

29.0 (25.0, 33.0)

0.873

Sodium (mmol/L)

140.0 (137.0, 142.0)

140.0 (137.0, 142.0)

140.0 (138.0, 142.0)

0.029

Creatinine (µmol/L)

58.0 (47.0, 71.3)

65.0 (54.0, 75.5)

52.0 (43.0, 63.8)

 < 0.001

PT-INR

1.3 (1.1, 1.4)

1.3 (1.2, 1.5)

1.2 (1.1, 1.4)

0.001

Complications, n (%)

 

0.084

 Ascites

239 (62.6)

124 (65.3)

115 (59.9)

 

 Hepatic encephalopathy

23 (6.0)

17 (8.9)

6 (3.1)

 

 GEVB

279 (73.0)

131 (68.9)

148 (77.1)

 

 Infection

43 (11.3)

21 (11.1)

22 (11.5)

 
  1. BMI body mass index, VATI visceral adipose tissue index, SATI subcutaneous adipose tissue index, SMI skeletal muscle index, CTP Child-Turcotte-Pugh, MAFLD metabolic dysfunction-associated fatty liver disease, MELD Model for End-stage Liver Disease, MELD-Na MELD-Sodium, AST aspartate aminotransferase, ALT alanine aminotransferase, PT-INR prothrombin time-international normalized ratio, GEVB gastroesophageal variceal bleeding
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