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Table 7 OLS regression of clinical characteristics on EQ-5D-5L and SF-6Dv2

From: EQ-5D-5L and SF-6Dv2 health utilities scores of diffuse large B-cell lymphoma patients in China

 

EQ-5D-5L

SF-6Dv2

Coef

(95% CI)

Coef

(95% CI)

Treatment status

 RR treatment

-0.017

-0.064

0.029

 

-0.005

-0.048

0.039

 

Whether on treatment

 Untreated

0.004

-0.29

0.298

 

-0.035

-0.312

0.242

 

 On treatment

-0.095

-0.142

-0.048

***

-0.138

-0.182

-0.093

***

Treatment evaluation

 PR

-0.033

-0.088

0.021

 

-0.046

-0.097

0.005

 

 PD

-0.104

-0.187

-0.021

*

-0.127

-0.205

-0.049

***

 Have not been evaluated

-0.055

-0.114

0.004

 

-0.07

-0.125

-0.015

*

IPI score

 IPI = 2 (medium risk)

0.012

-0.044

0.067

 

0.03

-0.022

0.082

 

 IPI = 3 ~ 5 (high risk)

-0.013

-0.07

0.045

 

0.009

-0.045

0.063

 

 Unknown

0.001

-0.056

0.054

 

0.004

-0.048

0.056

 

Double-hit/Triple-hit (DHL/THL)

 Yes

-0.042

-0.108

0.025

 

-

-

-

 

 Unknown

-0.012

-0.08

0.056

 

-

-

-

 

Double-expressor (DEL)

 Yes

-0.012

-0.058

0.034

 

-0.031

-0.072

0.009

 

 Unknown

-0.031

-0.1

0.038

 

-0.021

-0.065

0.023

 

TP53 mutation

 Yes

-0.017

-0.073

0.039

 

-0.005

-0.057

0.048

 

 Unknown

-0.02

-0.068

0.028

 

-0.018

-0.063

0.027

 

MYD88 mutation and/or CD79b mutation

 CD79b mutation

-0.004

-0.124

0.117

 

0.02

-0.093

0.132

 

 MYD88 mutation

-0.093

-0.175

-0.01

*

-0.082

-0.16

-0.005

*

 Both

-0.025

-0.104

0.053

 

-0.009

-0.083

0.065

 

 Unknown

0.01

-0.039

0.06

 

0.011

-0.035

0.057

 

Ann Arbor staging

 Stage II

-0.018

-0.08

0.045

 

-0.043

-0.102

0.016

 

 Stage III

-0.003

-0.074

0.069

 

-0.027

-0.094

0.04

 

 Stage IV

-0.076

-0.142

-0.011

*

-0.093

-0.155

-0.032

**

 Unknown

0.034

-0.107

0.04

 

-0.033

-0.102

0.036

 

Complication

 Have at least one complication

-0.035

-0.07

0

*

-0.054

-0.087

-0.021

***

Constant

0.959

0.904

1.014

***

0.789

0.737

0.84

***

  1. Reference category: initial treatment, off treatment, CR, IPI = 0 ~ 1 (low risk), no DHL/THL, no DEL, no TP53 mutation, neither MYD88 mutation nor CD79b mutation, Ann Arbor staging: Stage I, no complication
  2. *P < 0.05, **P < 0.01, ***P < 0.001