Table 2 Multiple regression of demographic and clinical characteristics with the course of the physical component of health-related quality of life after a SARS-CoV-2 infection

Sex

 Male

ref

ref

 Female

-0.90 (-2.94; 1.13)

0.38

Age

 18–53

ref

ref

 54 and over

0.39 (-1.61; 2.40)

0.70

Time

 Q1

ref

ref

 Q2

25.94 (15.65; 36.24)

< 0.01*

 Q3

27.96 (15.95; 39.97)

< 0.01*

Post-COVID condition

 No post-COVID condition

ref

ref

 Post-COVID condition

-7.02 (-9.11; -4.92)

< 0.01*

Physical HRQoL prior to SARS-CoV-2 infection

0.66 (0.46; 0.87)

< 0.01*

 Interaction time Q2

-0.45 (-0.64; -0.26)

< 0.01*

 Interaction time Q3

-0.50 (-0.72; -0.28)

< 0.01*

Self-perceived severity acute phase

 Hardly any to no symptoms

ref

ref

 Comparable to cold

-0.77 (-3.97; 2.42)

0.63

 Interaction time Q2

-1.01 (-4.09; 2.07)

0.52

 Interaction time Q3

0.01 (-3.53; 3.55)

1.00

 Very ill, but not hospitalized

-5.90 (-9.46; -2.35)

< 0.01*

 Interaction time Q2

1.72 (-1.59; 5.04)

0.31

 Interaction time Q3

4.38 (0.64; 8.11)

0.02*

 Hospitalized

-9.66 (-14.93; -4.40)

< 0.01*

 Interaction time Q2

5.93 (1.09; 10.77)

0.02*

 Interaction time Q3

6.83 (1.47; 12.19)

0.01*

Resilience

0.23 (0.05; 0.40)

0.01*

Body Mass Index

 18.5–25 (healthy weight)

ref

ref

 25–30 (overweight)

-1.89 (-4.02–0.24)

0.08

 > 30 (obese)

-3.09 (-6.23–0.05)

0.05