Table 3 Hypotheses to evaluate construct validity and responsiveness
1. Correlations with instruments measuring similar constructs should be ≥ 0.40 (positive) |
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2. Correlations with instruments measuring related, but dissimilar constructs should be lower, i.e. 0.10‐0.40 |
3. Correlations with instruments measuring unrelated constructs should be < 0.30 |
4. Correlations of change over time defined under 1, 2, and 3 should be mantained [responsiveness] |
5. Meaningful changes between relevant (sub)groups (e.g. patients with expected high vs low levels of HRQoL; pt with LARYNX ATTACKS, or EMERGENCY VISITS, or > N ATTACKS, inadeguate Long-term prophylaxis (LTP) will have significant lower HRQoL) |
6. For responsiveness, AUC should be ≥ 0.70 |