Table 5 Associations between EQ-5D-5L utility indexes & EQ-VAS and participant characteristics

PRIMARY EXPOSURES

Treatment stage

 Intensive phase

Ref

Ref

 Continuation phase

0.07

[0.04, 0.09]

< 0.001

4.3

[1.9, 6.6]

< 0.001

 End of treatment

0.16

[0.14, 0.19]

< 0.001

13.0

[8.9, 17.0]

< 0.001

Care pathway

 NTP

Ref

Ref

 ACF

0.07

[0.02, 0.13]

0.008

6.4

[5.2, 7.6]

< 0.001

 PPM

0.03

[-0.04, 0.10]

0.472

1.5

[-2.5, 5.5]

0.461

DEMOGRAPHICS

Sex

 Female

Ref

Ref

 Male

0.08

[0.05, 0.11]

< 0.001

2.5

[1.9, 3.1]

< 0.001

Age

 <35 years

Ref

Ref

 35–44 years

-0.11

[-0.12, -0.10]

< 0.001

-9.4

[-11.3, -7.5]

< 0.001

 45–54 years

-0.13

[-0.15, -0.10]

< 0.001

-8.3

[-9.9, -6.7]

< 0.001

 55–64 years

-0.15

[-0.18, -0.12]

< 0.001

-11.5

[-16.8, -6.3]

< 0.001

 65 + years

-0.18

[-0.21, -0.14]

< 0.001

-14.2

[-16.1, -12.3]

< 0.001

CLINICAL CHARACTERISTICS

Diagnosis

 Bacteriologically confirmed

Ref

Ref

 Clinically diagnosed

-0.04

[-0.11, 0.04]

0.369

-3.8

[-7.6, 0.0]

0.048

TB site

 Pulmonary TB

Ref

Ref

 Extrapulmonary TB

-0.14

[-0.43, 0.14]

0.315

-8.3

[-14.4, -2.2]

0.008

Treatment category

 New

Ref

Ref

 Retreatment

-0.07

[-0.08, -0.05]

< 0.001

-1.6

[-3.3, 0.1]

0.059

Treatment outcome

 Treatment success

Ref

Ref

 Unfavorable outcome*

0.01

[-0.07, 0.08]

0.868

-4.7

[-6.8, -2.7]

< 0.001

HEALTH ACCESS

Diagnostic delay

 1–3 weeks

Ref

Ref

 4–5 weeks

-0.05

[-0.08, -0.03]

< 0.001

-3.2

[-3.8, -2.6]

< 0.001

 6–10 weeks

-0.06

[-0.12, 0.00]

0.049

-3.7

[-5.1, -2.3]

< 0.001

 11–21 weeks

-0.11

[-0.14, -0.09]

< 0.001

-5.3

[-6.6, -4.0]

< 0.001

 22 + weeks

-0.09

[-0.12, -0.07]

< 0.001

-5.8

[-7.5, -4.0]

< 0.001

Health-seeking

 1–2 attempts

Ref

Ref

 3–4 attempts

0.05

[-0.05, 0.15]

0.344

0.0

[-5.9, 5.8]

0.992

 5–6 attempts

0.06

[-0.02, 0.14]

0.141

1.1

[-4.3, 6.5]

0.687

 7–10 attempts

0.09

[0.02, 0.15]

0.008

2.0

[-2.8, 6.8]

0.413

 11 + attempts

0.00

[-0.09, 0.10]

0.916

-0.5

[-4.4, 3.4]

0.804

Social Health Insurance

 No

Ref

Ref

 Yes

0.02

[-0.01, 0.05]

0.310

2.3

[1.8, 2.7]

< 0.001

SOCIOECONOMIC CHARACTERISTICS

Education level

 Not literate

Ref

Ref

 Primary school

0.14

[0.11, 0.18]

< 0.001

6.8

[4.9, 8.6]

< 0.001

 Secondary school

0.14

[0.10, 0.18]

< 0.001

6.5

[3.3, 9.7]

< 0.001

 High school

0.12

[-0.02, 0.25]

0.093

0.1

[-5.3, 5.6]

0.964

 University/Post-graduate

0.14

[-0.01, 0.30]

0.074

-1.2

[-5.6, 3.1]

0.575

Education length

 0–4 years

Ref

Ref

 5–6 years

-0.04

[-0.06, -0.01]

0.001

-1.8

[-2.7, -1.0]

< 0.001

 7–8 years

-0.01

[-0.04, 0.02]

0.544

-2.8

[-6.1, 0.5]

0.101

 9–11 years

-0.02

[-0.05, 0.01]

0.246

0.4

[-1.3, 2.1]

0.628

 12 + years

-0.02

[-0.19, 0.14]

0.762

9.5

[3.9, 15.0]

0.001

Head of household

 No

Ref

Ref

 Yes

0.03

[-0.01, 0.07]

0.124

0.9

[-0.6, 2.4]

0.233

Household size

 0–4 years

Ref

Ref

 5–6 years

-0.03

[-0.08, 0.01]

0.143

1.2

[0.0, 2.3]

0.044

 7–8 years

0.01

[-0.07, 0.09]

0.794

2.3

[-0.2, 4.7]

0.075

 9–11 years

0.03

[-0.04, 0.10]

0.380

2.5

[1.2, 3.7]

< 0.001

 12 + years

0.04

[-0.04, 0.12]

0.370

4.0

[2.4, 5.6]

< 0.001

Primary earner

 No

Ref

Ref

 Yes

-0.04

[-0.05, -0.02]

< 0.001

-0.8

[-1.8, 0.1]

0.090

Employment

 Unemployed

Ref

Ref

 Formally employed

0.05

[0.00, 0.10]

0.040

1.1

[-1.5, 3.6]

0.416

 Informally employed

0.04

[0.01, 0.08]

0.020

1.4

[0.1, 2.7]

0.039

 Don’t know/No answer

0.02

[-0.02, 0.06]

0.447

-0.6

[-1.6, 0.4]

0.252

Pre-TB monthly income

 USD 0–24

Ref

Ref

 USD 25–169

0.03

[-0.03, 0.09]

0.365

6.0

[3.4, 8.5]

< 0.001

 USD 170–259

0.03

[-0.03, 0.09]

0.357

4.6

[3.9, 5.2]

< 0.001

 USD 260–389

0.08

[0.03, 0.13]

0.001

4.2

[1.8, 6.6]

0.001

 USD 390+

0.04

[-0.03, 0.11]

0.300

6.5

[2.1, 10.9]

0.004

SOCIOECONOMIC IMPACT OF TB

Monthly income decline

 No decline

Ref

Ref

 USD 1-100

-0.07

[-0.12, -0.02]

0.004

-2.2

[-2.8, -1.7]

< 0.001

 USD 101–250

-0.07

[-0.10, -0.03]

< 0.001

-2.9

[-4.3, -1.4]

< 0.001

 USD 251–400

-0.08

[-0.11, -0.06]

< 0.001

-1.6

[-2.4, -0.8]

< 0.001

 USD 401+

-0.07

[-0.13, -0.01]

0.017

-4.2

[-7.2, -1.3]

0.005

Job loss

 No

Ref

Ref

 Yes

-0.04

[-0.10, 0.02]

0.178

-2.5

[-4.7, -0.2]

0.032

Borrow or receive cash

 No

Ref

Ref

 Yes

-0.04

[-0.07, 0.00]

0.027

-0.8

[-2.8, 1.3]

0.480

Sell assets

 No

Ref

Ref

 Yes

-0.03

[-0.07, 0.02]

0.249

-4.8

[-7.6, -2.1]

0.001